Although relatively uneducated, Redoute left home in what was then part of Luxembourg at the age of 13 to earn his living as an itinerant Belgian painter, doing interior decoration, portraits and religious commissions. Becoming acquainted with the work of Dutch flower painters Brueghel, Ruysch, van Huysum and de Heem, Redoute determined to become an heir to the tradition.
In 1782 Redoute joined his elder brother, an interior decorator and scenery designer in Paris. Cheveau, a Parisian dealer, brought the young artist to the attention of botanist, book lover Charles Louis L'H,ritier de Brutelle who greatly influenced his life and work thereafter.
Over his long career, Redoute painted the gardens at the Petite Trianon of Queen Marie-Antoinette as her official court artist and, during the revolution and Reign of Terror, he was appointed to document gardens which became national property. However, during the patronage of the generous Empress Josephine, Redoute's career flourished and he produced his most sumptuous books portraying plants from places as distant as Japan, South Africa and Australia as well as Europe and America.
After Josephine's death, Redoute's significant fortunes fell until appointed as a master of design for the Museum d'Histoire Naturelle in 1822 and awarded a Chevalier of the Legion d'Honneur in 1825. Although particularly renowned for his botanical exploration of roses and lilies, he thereafter produced paintings purely for aesthetic poses including the celebrated "Choix des plus belles Fleurs."